CLINICAL REPORT Parathyroid Lesions: Characterization with Dual-Phase Arterial and Venous Enhanced CT of the Neck

نویسنده

  • A. R. Gafton
چکیده

A.R. Gafton C.M. Glastonbury J.D. Eastwood J.K. Hoang SUMMARY: This clinical report describes the enhancement characteristics of hypersecreting parathyroid lesions on dual-phase neck CT. We retrospectively analyzed the enhancement characteristics of 5 pathologically confirmed PTH-secreting lesions on dual-phase CT examinations. Attenuation values were measured for PTH-secreting lesions, vascular structures (CCA and IJV), and soft tissue structures (thyroid gland, jugulodigastric lymph node, and submandibular gland). From the attenuation values, “relative enhancement washout percentage” and “tissue-vascular ratio” were calculated and compared. All lesions decreased in attenuation from arterial to venous phase, while the mean attenuation values of other soft tissue structures increased. A high relative enhancement washout percentage was correlated with parathyroid lesions (P .006). The tissue-CCA ratio and tissue-IJV ratio for PTHsecreting lesions in the arterial phase were statistically significantly higher compared with soft tissue structures (P .05). If these results are validated in future larger studies, noncontrast and delayed venous phases of 4D-CT could be eliminated to markedly reduce radiation exposure.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Parathyroid lesions: characterization with dual-phase arterial and venous enhanced CT of the neck.

This clinical report describes the enhancement characteristics of hypersecreting parathyroid lesions on dual-phase neck CT. We retrospectively analyzed the enhancement characteristics of 5 pathologically confirmed PTH-secreting lesions on dual-phase CT examinations. Attenuation values were measured for PTH-secreting lesions, vascular structures (CCA and IJV), and soft tissue structures (thyroid...

متن کامل

Dual-energy 4-phase CT scan in primary hyperparathyroidism.

We read with interest the article by Gafton et al published in 2012. The authors illustrated the use of a dual-phase CT protocol for the enhancement characterization of parathyroid lesions and suggested the elimination of precontrast and delayed scan phases from 4D CT to reduce radiation exposure. In this letter, we describe the alternative approach of our institution to 4D CT. Our modified 4D ...

متن کامل

Absent radiotracer uptake in thyroid gland in parathyroid scintigraphy with 99mTc-MIBI: A case report

Localization of 99mTc- hexakis-2-methoxyisobutylisonitrile (99mTc-MIBI) by parathyroid adenomas is well known, and this warrants MIBI scan to evaluate suspected parathyroid adenoma in primary hyperparathyroidism. Typically, the radionuclide concentrates in both the thyroid gland and parathyroid adenoma in early images, and later on delayed images washes out slowly from the...

متن کامل

Stereotactic Body Radiotherapy for Lung Lesions using Multiple Phase 3D-CT Based on the Analysis of Radiobiological Parameters

Introduction: Planning target volume (PTV) is generated from internal treatment volume (ITV) using four-dimensional computed tomography (4D-CT) for enhanced therapeutic gain in the stereotactic body radiotherapy for lung lesions (SBRT-Lung). This study aimed to propose a strategy to generate ITV on multiple-phase 3D-CT and enhance therapeutic gain in SBRT-Lung. <stron...

متن کامل

Single phase computed tomography is equivalent to dual phase method for localizing hyperfunctioning parathyroid glands in patients with primary hyperparathyroidism: a retrospective review

OBJECTIVE This study aims to compare the sensitivity of dual phase (non-contrast and arterial) versus single phase (arterial) CT for detection of hyper-functioning parathyroid glands in patients with primary hyperparathyroidism. METHODS The CT scans of thirty-two patients who have biochemical evidence of primary hyperparathyroidism, pathologically proven parathyroid adenomas, and pre-operativ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012